Southeastern Freight Lines
$55,000 - $85,000Local, Regional, LTL
Moderate Demand
Regional Truck Driver Jobs in South Carolina
Browse regional trucking positions across South Carolina with top carriers hiring now.
Pay
Ask the carrier
Demand Level
Moderate
Top Carriers
5+ Hiring
Key Cities
5+ Markets
Regional Trucking in South Carolina
South Carolina freight is led by the Port of Charleston and I-26 to Columbia/Greenville–Spartanburg, plus automotive plants along the I-85 Upstate corridor. Regional driver demand in South Carolina is moderate, with multi-state runs that usually keep drivers within a few hundred miles of a South Carolina domicile and weekly home time on many accounts.
Top Companies Hiring Regional Drivers in SC
View Company
ABF Freight (ArcBest)
$60,000 - $95,000Local, Regional, LTL
Amazon Freight
$60,000 - $95,000Local, Regional, Dedicated, Yard Jockey
Anderson Trucking Service
$65,000 - $95,000OTR, Regional, Flatbed, Specialized, Owner-Operator
Averitt Express
$55,000 - $85,000Local, Regional, LTL, Dedicated, Truckload
Driving job listings in South Carolina
These listings are not job offers from this website, and this site does not employ the driver. If a carrier is not named, the card is a description of a type of seat, not an offer of employment.
Dump Truck & Hotshot Flatbed Driver
Based on experience · Discussed on the call
OTR Dry Van Driver
$51,000 - $72,500/year · Out 2–3 weeks
OTR Reefer Driver
$56,000 - $79,000/year · Out 2–3 weeks
OTR Flatbed Driver
$57,500 - $81,000/year · Out 1–2 weeks
OTR Step Deck Driver
$58,500 - $82,500/year · Out 1–2 weeks
OTR Tanker Driver
$59,000 - $83,000/year · Out 1–2 weeks
OTR Hazmat Driver
$60,500 - $85,500/year · Out 1–2 weeks
OTR Car Hauler Driver
$61,500 - $87,000/year · Out 2–3 weeks
OTR Oversized Driver
$64,500 - $91,000/year · Out 2–3 weeks
Regional Intermodal Driver
$52,500 - $74,000/year · Home weekly
Local Box Truck Driver
$43,000 - $61,000/year · Home daily
Regional Dump Truck Driver
$48,500 - $69,000/year · Home most nights
Local Cement Mixer Truck Driver
$49,000 - $69,500/year · Home daily
OTR Hotshot Driver Driver
$53,500 - $75,500/year · Out 1–2 weeks
Regional Less Than Truckload Driver
$54,500 - $76,500/year · Home weekly
OTR Power Only Driver
$51,000 - $72,500/year · Out 2–3 weeks
Local Straight Truck Driver
$42,000 - $59,500/year · Home daily
Top Cities for Regional Jobs in South Carolina
Charleston
South Carolina
Columbia
South Carolina
Greenville
South Carolina
Spartanburg
South Carolina
Greer
South Carolina
Key Freight Routes in South Carolina
1
I-85 (Greenville-Spartanburg to Charlotte)
2
I-26 (Charleston to Columbia to Spartanburg)
3
I-95 (coastal corridor)
Requirements for Regional Driving in SC
- Valid CDL-A license
- 6+ months CDL-A experience (some carriers accept recent graduates)
- Clean MVR with no more than 2 moving violations in 3 years
- DOT physical card
- Willingness to travel multi-state routes within assigned region
- Pre-employment drug screen and background check
Start Your Regional Driving Career in South Carolina
Submit your application and get matched with companies hiring regional drivers in SC.
Regional Trucking Jobs in South Carolina — FAQs
How much do regional truck drivers make in South Carolina?
This page does not publish a dollar pay band for regional drivers in South Carolina. The figure that used to appear here was an unsourced regional multiplier, and every state in the same region showed the same band. Ask the carrier for the rate. Sign-on bonuses are widely advertised in this market, but the amount, the qualifying period and the clawback terms differ by carrier — read the offer letter rather than the recruiting ad, and ask when the money actually lands.
How often do regional drivers in South Carolina get home?
Most regional driving positions based in South Carolina offer weekly home time, with many carriers guaranteeing at least 34 hours off each week. Some premium regional accounts get drivers home every weekend. The frequency depends on the carrier, account, and your home terminal location relative to the regional freight lanes.
Are trucking companies in South Carolina hiring regional drivers in 2026?
Yes — regional driver demand in South Carolina is moderate heading into 2026. The regional segment in South Carolina is expanding, with carriers adding routes and increasing hiring as freight volumes grow. Check individual carrier listings for current openings and application requirements in SC.