Knight-Swift Transportation
$50,000 - $85,000OTR, Regional, Dedicated, Refrigerated, Intermodal
High Demand
Over-the-Road (OTR) Jobs in South Carolina
Browse otr trucking positions across South Carolina with top carriers hiring now.
Average Pay
$53,000 - $82,000
Demand Level
High
Top Carriers
5+ Hiring
Key Cities
5+ Markets
OTR Trucking in South Carolina
South Carolina benefits from a growing distribution network and year-round mild weather that keeps freight moving. OTR drivers based here haul consumer goods, automotive parts, and agricultural products throughout the eastern U.S. Demand for OTR drivers in South Carolina is high, with carriers actively recruiting experienced drivers and offering competitive sign-on bonuses. The state's strategic location keeps freight volumes consistent year-round.
Top Companies Hiring OTR Drivers in SC
View Company
Marten Transport
$55,000 - $85,000OTR, Regional, Dedicated, Refrigerated, Intermodal
KLLM Transport
$55,000 - $85,000OTR, Regional, Dedicated, Refrigerated
US Xpress (Knight-Swift)
$52,000 - $82,000OTR, Regional, Dedicated, Team
Forward Air
$60,000 - $90,000OTR, Regional, LTL, Expedited, Owner-Operator
Top Cities for OTR Jobs in South Carolina
Greenville
South Carolina
Columbia
South Carolina
Spartanburg
South Carolina
Florence
South Carolina
Charleston
South Carolina
Key Freight Routes in South Carolina
1
I-85 (Greenville-Spartanburg to Charlotte)
2
I-26 (Charleston to Columbia to Spartanburg)
3
I-95 (coastal corridor)
Requirements for OTR Driving in SC
- Valid CDL-A license
- Minimum 6 months verifiable OTR experience (some carriers accept new graduates)
- Clean MVR with no major violations in the past 3 years
- DOT physical card (medical examiner's certificate)
- Ability to pass pre-employment drug screening
- Must be at least 21 years old for interstate driving
Start Your OTR Driving Career in South Carolina
Submit your application and get matched with companies hiring otr drivers in SC.
OTR Trucking Jobs in South Carolina — FAQs
How much do otr truck drivers make in South Carolina?
OTR truck drivers in South Carolina earn $53,000 - $82,000 annually, depending on experience, endorsements, and carrier. While base pay in South Carolina is near the national average, the lower cost of living means take-home pay stretches further than in coastal states. Sign-on bonuses of $3,000 to $15,000 are common at major carriers actively hiring in SC.
What are the best OTR trucking routes through South Carolina?
South Carolina's interstate system connects drivers to major freight lanes across the region. Outbound loads from South Carolina typically move to distribution hubs in neighboring states, while inbound freight includes consumer goods, raw materials, and manufacturing inputs. Carriers based in or running through SC offer consistent miles with multiple routing options.
Are trucking companies in South Carolina hiring otr drivers in 2026?
Yes — otr driver demand in South Carolina is high heading into 2026. Carriers operating in South Carolina are actively recruiting otr drivers with competitive pay packages and benefits to fill open positions. Check individual carrier listings for current openings and application requirements in SC.