Regional Truck Driver Jobs in South Carolina
Browse regional trucking positions across South Carolina with top carriers hiring now.
Average Pay
$53,000 - $78,000
Demand Level
High
Top Carriers
5+ Hiring
Key Cities
5+ Markets
Regional Trucking in South Carolina
South Carolina-based regional drivers cover the Southeast freight belt, running lanes through the Carolinas, Georgia, Florida, and Tennessee. The region's manufacturing and distribution growth keeps freight volumes strong. Regional driver demand in South Carolina is high, with most positions offering weekly home time and steady freight.
Top Companies Hiring Regional Drivers in SC
Old Dominion Freight Line
Estes Express Lines
ABF Freight (ArcBest)
Walmart Transportation
Top Cities for Regional Jobs in South Carolina
Columbia
South Carolina
Greenville
South Carolina
Spartanburg
South Carolina
Florence
South Carolina
Charleston
South Carolina
Key Freight Routes in South Carolina
I-85 (Greenville-Spartanburg to Charlotte)
I-26 (Charleston to Columbia to Spartanburg)
I-95 (coastal corridor)
Requirements for Regional Driving in SC
- Valid CDL-A license
- 6+ months CDL-A experience (some carriers accept recent graduates)
- Clean MVR with no more than 2 moving violations in 3 years
- DOT physical card
- Willingness to travel multi-state routes within assigned region
- Pre-employment drug screen and background check
Start Your Regional Driving Career in South Carolina
Submit your application and get matched with companies hiring regional drivers in SC.
Regional Trucking Jobs in South Carolina — FAQs
How much do regional truck drivers make in South Carolina?
Regional truck drivers in South Carolina earn $53,000 - $78,000 annually, depending on experience, endorsements, and carrier. While base pay in South Carolina is near the national average, the lower cost of living means take-home pay stretches further than in coastal states. Sign-on bonuses of $3,000 to $15,000 are common at major carriers actively hiring in SC.
How often do regional drivers in South Carolina get home?
Most regional driving positions based in South Carolina offer weekly home time, with many carriers guaranteeing at least 34 hours off each week. Some premium regional accounts get drivers home every weekend. The frequency depends on the carrier, account, and your home terminal location relative to the regional freight lanes.
Are trucking companies in South Carolina hiring regional drivers in 2026?
Yes — regional driver demand in South Carolina is high heading into 2026. Carriers operating in South Carolina are actively recruiting regional drivers with competitive pay packages and benefits to fill open positions. Check individual carrier listings for current openings and application requirements in SC.