KLLM Transport
$55,000 - $85,000OTR, Regional, Dedicated, Refrigerated
Growing Demand
Regional Truck Driver Jobs in Mississippi
Browse regional trucking positions across Mississippi with top carriers hiring now.
Average Pay
$53,000 - $78,000
Demand Level
Growing
Top Carriers
5+ Hiring
Key Cities
5+ Markets
Regional Trucking in Mississippi
Mississippi-based regional drivers cover the Southeast freight belt, running lanes through the Carolinas, Georgia, Florida, and Tennessee. The region's manufacturing and distribution growth keeps freight volumes strong. Regional driver demand in Mississippi is growing, with most positions offering weekly home time and steady freight.
Top Companies Hiring Regional Drivers in MS
View Company
Knight-Swift Transportation
$50,000 - $85,000OTR, Regional, Dedicated, Refrigerated, Intermodal
USA Truck (DB Schenker)
$50,000 - $75,000OTR, Regional, Dedicated
Old Dominion Freight Line
$65,000 - $100,000+Local, Regional, LTL
TForce Freight (formerly UPS Freight)
$60,000 - $90,000Local, Regional, LTL
Top Cities for Regional Jobs in Mississippi
Tupelo
Mississippi
Southaven
Mississippi
Meridian
Mississippi
Jackson
Mississippi
Gulfport
Mississippi
Key Freight Routes in Mississippi
1
I-55 (Jackson to Memphis and New Orleans)
2
I-20 (Jackson to Meridian and Vicksburg)
3
I-10 (Gulf Coast)
Requirements for Regional Driving in MS
- Valid CDL-A license
- 6+ months CDL-A experience (some carriers accept recent graduates)
- Clean MVR with no more than 2 moving violations in 3 years
- DOT physical card
- Willingness to travel multi-state routes within assigned region
- Pre-employment drug screen and background check
Start Your Regional Driving Career in Mississippi
Submit your application and get matched with companies hiring regional drivers in MS.
Regional Trucking Jobs in Mississippi — FAQs
How much do regional truck drivers make in Mississippi?
Regional truck drivers in Mississippi earn $53,000 - $78,000 annually, depending on experience, endorsements, and carrier. While base pay in Mississippi is near the national average, the lower cost of living means take-home pay stretches further than in coastal states. Sign-on bonuses of $3,000 to $15,000 are common at major carriers actively hiring in MS.
How often do regional drivers in Mississippi get home?
Most regional driving positions based in Mississippi offer weekly home time, with many carriers guaranteeing at least 34 hours off each week. Some premium regional accounts get drivers home every weekend. The frequency depends on the carrier, account, and your home terminal location relative to the regional freight lanes.
Are trucking companies in Mississippi hiring regional drivers in 2026?
Yes — regional driver demand in Mississippi is growing heading into 2026. The regional segment in Mississippi is expanding, with carriers adding routes and increasing hiring as freight volumes grow. Check individual carrier listings for current openings and application requirements in MS.