Over-the-Road (OTR) Jobs in Mississippi
Browse otr trucking positions across Mississippi with top carriers hiring now.
Average Pay
$53,000 - $82,000
Demand Level
Growing
Top Carriers
5+ Hiring
Key Cities
5+ Markets
OTR Trucking in Mississippi
Mississippi benefits from a growing distribution network and year-round mild weather that keeps freight moving. OTR drivers based here haul consumer goods, automotive parts, and agricultural products throughout the eastern U.S. Demand for OTR drivers in Mississippi is growing, with carriers actively recruiting experienced drivers and offering competitive sign-on bonuses. The state's strategic location keeps freight volumes consistent year-round.
Top Companies Hiring OTR Drivers in MS
Landstar System
Mercer Transportation
Marten Transport
US Xpress (Knight-Swift)
Top Cities for OTR Jobs in Mississippi
Gulfport
Mississippi
Hattiesburg
Mississippi
Southaven
Mississippi
Jackson
Mississippi
Tupelo
Mississippi
Key Freight Routes in Mississippi
I-55 (Jackson to Memphis and New Orleans)
I-20 (Jackson to Meridian and Vicksburg)
I-10 (Gulf Coast)
Requirements for OTR Driving in MS
- Valid CDL-A license
- Minimum 6 months verifiable OTR experience (some carriers accept new graduates)
- Clean MVR with no major violations in the past 3 years
- DOT physical card (medical examiner's certificate)
- Ability to pass pre-employment drug screening
- Must be at least 21 years old for interstate driving
Start Your OTR Driving Career in Mississippi
Submit your application and get matched with companies hiring otr drivers in MS.
OTR Trucking Jobs in Mississippi — FAQs
How much do otr truck drivers make in Mississippi?
OTR truck drivers in Mississippi earn $53,000 - $82,000 annually, depending on experience, endorsements, and carrier. While base pay in Mississippi is near the national average, the lower cost of living means take-home pay stretches further than in coastal states. Sign-on bonuses of $3,000 to $15,000 are common at major carriers actively hiring in MS.
What are the best OTR trucking routes through Mississippi?
Mississippi's interstate system connects drivers to major freight lanes across the region. Outbound loads from Mississippi typically move to distribution hubs in neighboring states, while inbound freight includes consumer goods, raw materials, and manufacturing inputs. Carriers based in or running through MS offer consistent miles with multiple routing options.
Are trucking companies in Mississippi hiring otr drivers in 2026?
Yes — otr driver demand in Mississippi is growing heading into 2026. The otr segment in Mississippi is expanding, with carriers adding routes and increasing hiring as freight volumes grow. Check individual carrier listings for current openings and application requirements in MS.